Jonathan Sosnov M.D. Nephrologist

Division of Nephrology and Hypertension

Department of Medicine
University of Miami Miller School of Medicine
Miami, FL 33136

jsosnov [at] med [dot] miami [dot] edu

Position: Assistant Professor of Clinical Medicine

University of Miami Miller School of Medicine, Department of Medicine, Division of Nephrology and Hypertension

Fields: Decision Analysis, Cost-Effectiveness Analysis, Meta-analysis, Kidney Disease Epidemiology

MISSION

Program for Evidence and Knowledge in Medicine

Medicine has reached a crossroad. The Evidence-Based Medicine movement has created a set of rules for identifying what can be considered knowledge in medicine, but its critics have worried about the logical and ethical results of its premises. Yet, it remains the only explicit, formal, wide-scale system of determining the quality of evidence in medicine in use.

The Program on Evidence and Knowledge in Medicine seeks to:

1. Understand how evidence and knowledge are currently used in medicine.

2. Explore methodologies to evaluate evidence and knowledge in medicine.

3. Apply these theoretical results to medical decision-making.

4. Explore the theoretical implications and measure how these theories affect the practice of medicine.

5. Improve the care of patients through a better understanding of evidence and knowledge in medicine.

This will be achieved by the collaboration of faculty members across the University of Miami. We will create and test new methodologies of evaluating strategies of justification in medicine. We will propagate results via peer-review publications, conferences, workshops, courses offered in connection with various departments, and invited lectures and seminars.

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ACP Observer, May 2006 - Part D hopes and hassles begin to play out
"There are more than 170 plans in Florida, so you can imagine being [age] 85 ... by Dr. Pauker and nephrologists Jonathan Sosnov MD, and Klemens Meyer, MD.

TRANS2D1 Frontmatter.p65
University of Florida, Gainesville, FL. It has been previously reported that the serum creatinine (Scr) at one year after renal ... Jonathan A. Sosnov Alumni Jonathan Sosnov, MD, MS Differential Symptoms of Acute Myocardial Infarction in Patients with Kidney Disease: A Community-Wide Perspective Symptoms of AMI ...
www.nemc.org/icrhps/gradprog/sacklermsphd/alumini.asp

Tufts-New England Medical Center
Magdalena Madero, MD. Ashish Mahajan, MD. Essam Elsayed, MD. Yasser Nasser, MD. Jonathan Sosnov, MD. Dena Rifkin, MD. Jill Young, MD. Ron Wald, MD ...
www.nemc.org/nephrology/fellows.asp

ACP Observer, May 2006 - Part D hopes and hassles begin to play out
A recent pilot survey of Boston-area physicians conducted by Dr. Pauker and nephrologists Jonathan Sosnov, MD, and Klemens Meyer, MD, found that only 53% of ...
www.acponline.org/journals/news/may06/partd.htm

[PDF] William B Schwartz MD Division of Nephrology
Jonathan Sosnov MD Clinical Fellow, William B. Schwartz Division of. Nephrology Tufts-New ... Jonathan Sosnov MD. 2003 – 2004. Research Fellow ...
www.tufts-nemc.org/nephrology/documents/Nephrology%202004%20Annual%20Report.pdf

Cardiology
Jonathan Sosnov of Tufts-New England Medical Center, Boston, and his associates. More patients with kidney disease die from cardiovascular causes than from ...
www.acep.org/webportal/MemberCenter/Periodicals/Medical+News/Cardiology/default.htm?newsid=0c022fee

Polish Bioinformatics Site
Jonathan Sosnov, Darleen Lessard, Robert J Goldberg, Jorge Yarzebski, Joel M Gore. BACKGROUND: Patients seeking care for acute myocardial infarction (AMI

[PDF] TRANS2D1 Frontmatter.p65
KIDNEY TRANSPLANTATION EVALUATION. ANALYSIS USING A DOMAIN ELIMINATION. THEORY. (Abstract #594). Jonathan A. Sosnov, Richard E. Wing, Martin S. Zand

Am J Kidney Dis. 2006 Mar ;47:378-84
Differential symptoms of acute myocardial infarction in patients with kidney disease: a community-wide perspective.
Jonathan Sosnov, Darleen Lessard, Robrt J Goldberg, Jorge Yarzebski, Joel M Gore
BACKGROUND: Patients seeking care for acute myocardial infarction (AMI) present with multiple symptoms. The objectives of our community-wide study are to examine the symptom profile of patients with, as compared with those without, kidney disease who present to the hospital with independently confirmed AMI. METHODS: The symptom profile of 4,482 patients from the Worcester, MA, metropolitan area hospitalized with independently validated AMI at all 11 area medical centers during the 4 study years of 1997, 1999, 2001, and 2003 was examined. Factor analysis was used to aggregate the relevant symptoms of AMI. Logistic regression analysis was used to examine differences in symptoms of AMI according to the presence of kidney disease while controlling for several potentially confounding demographic and clinical factors. RESULTS: Patients with kidney disease were less likely to report chest pain (adjusted odds ratio, 0.57; 95% confidence interval, 0.46 to 0.70), arm pain (odds ratio, 0.52; 95% confidence interval, 0.42 to 0.64), shoulder pain (odds ratio, 0.53; 95% confidence interval, 0.40 to 0.72), or neck pain (odds ratio, 0.54; 95% confidence interval, 0.41 to 0.70), while being more likely to report shortness of breath (odds ratio, 1.35; 95% confidence interval, 1.13 to 1.62), in comparison to patients without kidney disease in the setting of AMI. CONCLUSION: Kidney disease impacts on the manner in which patients present with AMI. Although patients with kidney disease are at known increased risk for several diseases, this study suggests that kidney disease also might change how these patients experience these diseases, including acute coronary disease.

Internal Medicine News: MI presentation different in kidney ...
People with kidney disease have a somewhat different symptom profile.
When they present with acute myocardial infarction than those without kidney disease, reported Dr. Jonathan Sosnov of Tufts--New England Medical Center, Boston, and his associates.
More patients with kidney disease die from cardiovascular causes than from any other cause. "Accurate and rapid diagnosis of MI in these high-risk patients might decrease their risk for subsequent morbidity and mortality by providing definitive treatment in a more timely manner," the investigators said.